CS and GS Benefits for Other Diseases
Discat Plus ENHANCED has CHONDROITIN SULFATE (from perna canaliculus which is reportedly the “single most effective” item for relief of joint pain and inflammation as occurs with disc herniation, osteoarthritis, and rheumatoid arthritis). (33) Researchers observed that patients experience 77% reduced inflammation vs. only 42% with NSAIDs. (33) Chondroitin sulfate fights inflammation. (40) Its proteoglycans function in the central nervous system to regulate cell adhesion and migration, neurite formation, etc. (41) It is the glycosaminoglycan part of the disc that stimulates its synthesis and imbibes water up to 9X its own volume.
It has GLUCOSAMINE SULFATE (a naturally occurring part of joint cartilage) which lends its anti-inflammatory property to the mix.
And you’ll note both are tied to sulfate which acts like a “magnet” to attract fluid into the proteoglycan molecules to form cartilage. Important!
They are beneficial for other diseases.
- CS (alone or in combination with glucosamine) was better than placebo in improving pain in participants with osteoarthritis in short-term studies. (76) CS combines structure-modifying and symptom-modifying effects on osteoarthritis progression prevention and suggests it could be a disease-modifying agent in patients with knee arthritis. (77) CS benefits symptomatic osteoarthritis (OA) of the finger, knee, hip joints, low back, facial joints and other diseases due to its anti-inflammatory activity. (56)
- It has slight to moderate efficacy with an excellent safety profile. (78)
- Hypertension is noticeably reduced with CS. (73)
- GAG/CS may direct the movement of trigeminal nerve growth cones innervating the cornea. (79)
- Use of glucosamine and chondroitin supplements may lower risk of colorectal cancer by 45% over non-users. (80,81,82)
- High 10-year use of glucosamine but not chondroitin was associated with a reduction in lung cancer risk (adenocarcinoma). (83) Any use of glucosamine and chondroitin over the previous 10 years was associated with significantly lower lung cancer risk. (84)
It also has NUTRIENTS FOUND IN THE NORMAL DISC naturally - calcium, magnesium, manganese, potassium, and zinc - to support the health of the disc.