RNAs have been in the news lately, so this study takes a little twist on the role of RNA in spine disease. Circulating microRNAs can give a glimpse of current disease states. In healthy versus disc disease patients, those with disc disease were found to have significantly downregulated levels of miR-155-5p. It's an accurate diagnostic predictor for the presence of degeneration. Bottomline: Degenerative disc disease patients may have a special biomarker indicating that they have degenerative disc disease:  SERUM MIR-155-5P. The blood tells much..and may be an early indicator of disc disease! Read more about this finding.
from: Divi SN, Markova DZ, Fang T, et al. Circulating miR-155-5p as a Novel Biomarker of Lumbar Degenerative Disc Disease. Spine (Phila Pa 1976). 2020;45(9):E499–E507

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